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1

KMT2D Mutation Is Associated With Poor Prognosis in Non–Small-Cell Lung Cancer

Ardeshir-Larijani, Fatemeh, Bhateja, Priyanka, Lipka, Mary Beth, Sharma, Neelesh, Fu, Pingfu, Dowlati, Afshin

Journal:

Clinical Lung Cancer

Year:

2018

Language:

english

File:

PDF, 1.61 MB

english, 2018

2

NCCN Guidelines Insights: Small Cell Lung Cancer, Version 2.2018

Kalemkerian, Gregory P., Loo, Billy W., Akerley, Wallace, Attia, Albert, Bassetti, Michael, Boumber, Yanis, Decker, Roy, Dobelbower, M. Chris, Dowlati, Afshin, Downey, Robert J., Florsheim, Charles, G

Journal:

Journal of the National Comprehensive Cancer Network

Year:

2018

Language:

english

File:

PDF, 323 KB

english, 2018

3

Molecular subtypes of small cell lung cancer: a synthesis of human and mouse model data

Rudin, Charles M., Poirier, John T., Byers, Lauren Averett, Dive, Caroline, Dowlati, Afshin, George, Julie, Heymach, John V., Johnson, Jane E., Lehman, Jonathan M., MacPherson, David, Massion, Pierre

Journal:

Nature Reviews Cancer

Year:

2019

Language:

english

File:

PDF, 1.08 MB

english, 2019

4

A multi-center phase II study of oxaliplatin, irinotecan, and capecitabine in advanced gastric/gastroesophageal junction carcinoma

Joanna M. Brell, Smitha S. Krishnamurthi, Milind Javle, Joel Saltzman, Ira Wollner, Robert Pelley, Afshin Dowlati, Belagodu N. Kantharaj, Mark D. Schluchter, Linda Rath, S. Percy Ivy, Scot C. Remick

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2009

Language:

english

File:

PDF, 277 KB

english, 2009

5

Paclitaxel–Carboplatin Alone or with Bevacizumab for Non–Small-Cell Lung Cancer

Sandler, Alan, Gray, Robert, Perry, Michael C., Brahmer, Julie, Schiller, Joan H., Dowlati, Afshin, Lilenbaum, Rogerio, Johnson, David H.

Journal:

Boston Medical and Surgical Journal

Year:

2006

Language:

english

File:

PDF, 236 KB

english, 2006

6

Effect of Hormone Replacement Therapy for Menopause on the Mechanical Properties of Skin

Piérard, Gérald E., Letawe, Caroline, Dowlati, Afshin, Piérard-Franchimont, Claudine

Journal:

Journal of the American Geriatrics Society

Year:

1995

Language:

english

File:

PDF, 366 KB

english, 1995

7

The FACT inhibitor CBL0137 synergizes with cisplatin in small cell lung cancer by increasing NOTCH1 expression and targeting tumor-initiating cells

De, Sarmishtha, Lindner, Daniel J, Coleman, Claire, Wildey, Gary, Dowlati, Afshin, Stark, George R.

Journal:

Cancer Research

Year:

2018

Language:

english

File:

PDF, 2.09 MB

english, 2018

8

Immunotherapy in EGFR mutant non-small cell lung cancer: when, who and how?

Bruno, Debora, Dowlati, Afshin

Journal:

Translational Lung Cancer Research

Year:

2019

Language:

english

File:

PDF, 149 KB

english, 2019

9

High neuron specific enolase levels in bronchoalveolar lavage fluid of patients with lung carcinoma: Diagnostic value, relation to serum neuron specific enolase, and staging

Afshin Dowlati, Thierry Bury, Jean Louis Corhay, Thierry Weber, Pedro Mendes, Maurice Radermecker

Journal:

Year:

1996

Language:

english

File:

PDF, 463 KB

english, 1996

10

Phase II study of bryostatin 1 and vincristine for aggressive non-Hodgkin lymphoma relapsing after an autologous stem cell transplant

Paul M. Barr, Hillard M. Lazarus, Brenda W. Cooper, Mark D. Schluchter, Ashok Panneerselvam, James W. Jacobberger, Jack W. Hsu, Nalini Janakiraman, Aleksandra Simic, Afshin Dowlati, Scot C. Remick

Journal:

American Journal of Hematology

Year:

2009

Language:

english

File:

PDF, 115 KB

english, 2009

11

Cooperative interaction between protein inhibitor of activated signal transducer and activator of transcription-3 with epidermal growth factor receptor blockade in lung cancer

Amy Kluge, Snehal Dabir, Jeffrey Kern, David Nethery, Balazs Halmos, Patrick Ma, Afshin Dowlati

Journal:

International Journal of Cancer

Year:

2009

Language:

english

File:

PDF, 377 KB

english, 2009

12

Anaemia of lung cancer is due to impaired erythroid marrow response to erythropoietin stimulation as well as relative inadequacy of erythropoietin production

Afshin Dowlati, Samir R'Zik, Georges Fillet, Yves Beguin

Journal:

British Journal of Haematology

Year:

1997

Language:

english

File:

PDF, 318 KB

english, 1997

13

A phase IB clinical and pharmacokinetic study of the angiogenesis inhibitor SU5416 and paclitaxel in recurrent or metastatic carcinoma of the head and neck

Matthew M. Cooney, Kou-Yi Tserng, Vinit Makar, R. Jeff McPeak, Stephen T. Ingalls, Afshin Dowlati, Beth Overmoyer, Keith McCrae, Pamela Ksenich, Pierre Lavertu, Percy Ivy, Charles L. Hoppel, Scot Remi

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2005

Language:

english

File:

PDF, 233 KB

english, 2005

14

Phase I clinical and pharmacokinetic study of oxaliplatin, irinotecan and capecitabine

Smitha S. Krishnamurthi, Joanna M. Brell, Charles L. Hoppel, Merrill J. Egorin, Karen C. Weaver, Xiaolin Li, Stephen T. Ingalls, Eleanor G. Zuhowski, Mark D. Schluchter, Afshin Dowlati, Matthew M. Coo

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2009

Language:

english

File:

PDF, 487 KB

english, 2009

15

Phase II and pharmacokinetic trial of rebeccamycin analog in advanced biliary cancers

Afshin Dowlati, James Posey, Ramesh K. Ramanathan, Linda Rath, Pingfu Fu, Amitabh Chak, Smitha Krishnamurthi, Joanna Brell, Stephen Ingalls, Charles L. Hoppel, Percy Ivy, Scot C. Remick

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2009

Language:

english

File:

PDF, 274 KB

english, 2009

16

Phase II and pharmacokinetic/pharmacodynamic trial of sequential topoisomerase I and II inhibition with topotecan and etoposide in advanced non-small-cell lung cancer

Afshin Dowlati, Nathan Levitan, Nahida H. Gordon, Charles L. Hoppel, David M. Gosky, Scot C. Remick, Stephen T. Ingalls, Sossamma J. Berger, Nathan A. Berger

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2001

Language:

english

File:

PDF, 125 KB

english, 2001

17

Randomized phase II trial of different schedules of administration of rebeccamycin analogue as second line therapy in non-small cell lung cancer

Afshin Dowlati, Robert Chapman, Shanmuga Subbiah, Pingfu Fu, Anne Ness, Tania Cortas, Lauren Patrick, Sherrie Reynolds, Natalie Xu, Nathan Levitan, Percy Ivy, Scot C. Remick

Journal:

Investigational New Drugs

Year:

2005

Language:

english

File:

PDF, 125 KB

english, 2005

18

Phase I trial of docetaxel and thalidomide: a regimen based on metronomic therapeutic principles

Sharon L. Sanborn, Matthew M. Cooney, Afshin Dowlati, Joanna M. Brell, Smitha Krishnamurthi, Joseph Gibbons, Joseph A. Bokar, Charles Nock, Anne Ness, Scot C. Remick

Journal:

Investigational New Drugs

Year:

2008

Language:

english

File:

PDF, 146 KB

english, 2008

19

Phase I trial of docetaxel given every 3

Sharon L. Sanborn, Joseph Gibbons, Smitha Krishnamurthi, Joanna M. Brell, Afshin Dowlati, Joseph A. Bokar, Charles Nock, Nancy Horvath, Jacob Bako, Scot C. Remick, Matthew M. Cooney

Journal:

Investigational New Drugs

Year:

2009

Language:

english

File:

PDF, 153 KB

english, 2009

20

A phase I study of rebeccamycin analog in combination with oxaliplatin in patients with refractory solid tumors

Charles J. Nock, Joanna M. Brell, Joseph A. Bokar, Matthew M. Cooney, Brenda Cooper, Joseph Gibbons, Smitha Krishnamurthi, Sudhir Manda, Panayiotis Savvides, Scot C. Remick, Percy Ivy, Afshin Dowlati

Journal:

Investigational New Drugs

Year:

2011

Language:

english

File:

PDF, 105 KB

english, 2011

21

Temporal evolution of patient characteristics enrolled on phase I trials

Afshin Dowlati, Madappa Kundranda, Sudhir Manda, Lauren Patrick, Pingfu Fu

Journal:

Investigational New Drugs

Year:

2011

Language:

english

File:

PDF, 112 KB

english, 2011

22

Phase I trial of fludarabine, bortezomib and rituximab for relapsed and refractory indolent and mantle cell non-Hodgkin lymphoma

Paul M. Barr, Pingfu Fu, Hillard M. Lazarus, Nancy Horvath, Stanton L. Gerson, Omer N. Koc, Nizar J. Bahlis, Michael R. Snell, Afshin Dowlati, Brenda W. Cooper

Journal:

British Journal of Haematology

Year:

2009

Language:

english

File:

PDF, 91 KB

english, 2009

23

EFFECTS OF SOFTFNFD AND UNSOFTFNED FABRICS ON INFANT SKIN

GERALD E. PIÉRARD, JORGE E. ARRESE, AFSHIN DOWLATI, PANAGIOTIS A. DASKALEROS, CARLOS RODRIGUEZ

Journal:

International Journal of Dermatology

Year:

1994

Language:

english

File:

PDF, 3.64 MB

english, 1994

24

From COX-2 inhibitor nimesulide to potent anti-cancer agent: Synthesis, in vitro, in vivo and pharmacokinetic evaluation

Bo Zhong, Xiaohan Cai, Snigdha Chennamaneni, Xin Yi, Lili Liu, John J. Pink, Afshin Dowlati, Yan Xu, Aimin Zhou, Bin Su

Journal:

European Journal of Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 2.33 MB

english, 2012

25

Five-year survival does not equal cure in non–small cell lung cancer: A Surveillance, Epidemiology, and End Results–based analysis of variables affecting 10- to 18-year survival

Matthew O. Hubbard, Pingfu Fu, Seunghee Margevicius, Afshin Dowlati, Philip A. Linden

Journal:

The Journal of Thoracic and Cardiovascular Surgery

Year:

2012

Language:

english

File:

PDF, 198 KB

english, 2012

26

Evaluation of interleukin-6 in bronchoalveolar lavage fluid and serum of patients with lung cancer

Afshin Dowlati, Nathan Levitan, Scot C Remick

Journal:

Journal of Laboratory and Clinical Medicine

Year:

1999

Language:

english

File:

PDF, 450 KB

english, 1999

27

Identification of a Class of Novel Tubulin Inhibitors

Geldenhuys, Werner J., Feng, Ye, Pink, John J., Dowlati, Afshin, Xu, Yan, Zhou, Aimin, Su, Bin, Yi, Xin, Zhong, Bo, Smith, Kerri M.

Journal:

Journal of Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 4.07 MB

english, 2012

28

Phase I clinical trials in patients ≥ 80

Himabindu Gaddipati, Pingfu Fu, Afshin Dowlati

Journal:

Journal of Geriatric Oncology

Year:

2011

Language:

english

File:

PDF, 171 KB

english, 2011

29

Human herpesvirus-8–associated disseminated angiosarcoma in an HIV-seronegative woman: report of a case and limited case-control virologic study in vascular tumors

Scot C Remick, Madhumita Patnaik, Navid M Ziran, Karsten R Liegmann, Jennifer Dong, Afshin Dowlati, Yao Yao, Fadi W Abdul-Karim, Chou-Zen Giam

Journal:

The American Journal of Medicine

Year:

2000

Language:

english

File:

PDF, 168 KB

english, 2000

30

Phase I trials of targeted anticancer drugs: a need to refocus

Borden, Ernest C., Dowlati, Afshin

Journal:

Nature Reviews Drug Discovery

Year:

2012

Language:

english

File:

PDF, 89 KB

english, 2012

31

Paclitaxel added to the cisplatin/etoposide regimen in extensive-stage small cell lung cancer — the use of complete response rate as the primary endpoint in phase II trials

Dowlati, Afshin, Crosby, Lori, Remick, Scot C., Makkar, Vinit, Levitan, Nathan

Journal:

Year:

2001

Language:

english

File:

PDF, 80 KB

english, 2001

32

Combination chemotherapy with topotecan for non-small cell lung cancer

Dowlati, Afshin, Levitan, Nathan

Journal:

Year:

2003

Language:

english

File:

PDF, 513 KB

english, 2003

33

A brief intensive cisplatin-based outpatient chemotherapy regimen with filgrastim and megestrol acetate support for advanced non-small cell lung cancer: results of a phase II trial

Levitan, Nathan, Dowlati, Afshin, Craffey, Mark, Tahsildar, Hassan, MacKay, Wilma, McKenney, John, Remick, Scot C.

Journal:

Year:

1998

Language:

english

File:

PDF, 94 KB

english, 1998

34

Activation state egfr and STAT-3 as prognostic markers in resected non-small cell lung cancer

Cortas, Tania, Eisenberg, Rosana, Fu, Pingfu, Kern, Jeffrey, Patrick, Lauren, Dowlati, Afshin

Journal:

Year:

2007

Language:

english

File:

PDF, 511 KB

english, 2007

35

Phase II trial of thalidomide as maintenance therapy for extensive stage small cell lung cancer after response to chemotherapy

Dowlati, Afshin, Subbiah, Shanmuga, Cooney, Matthew, Rutherford, Kimberly, Mekhail, Tarek, Fu, Pingfu, Chapman, Robert, Ness, Anne, Cortas, Tania, Saltzman, Joel, Levitan, Nathan, Warren, Gregory

Journal:

Year:

2007

Language:

english

File:

PDF, 174 KB

english, 2007

36

Protein inhibitor of activated STAT3 expression in lung cancer

Amy Kluge, Snehal Dabir, Ilse Vlassenbroeck, Rosana Eisenberg, Afshin Dowlati

Journal:

Molecular Oncology

Year:

2011

Language:

english

File:

PDF, 1.32 MB

english, 2011

37

Ongoing Trials with Bevacizumab and Other Antiangiogenic Agents in Lung Cancer

Journal:

Clinical Lung Cancer

Year:

2008

Language:

english

File:

PDF, 123 KB

english, 2008

38

Synthesis and Anticancer Mechanism Investigation of Dual Hsp27 and Tubulin Inhibitors

Zhong, Bo, Chennamaneni, Snigdha, Lama, Rati, Yi, Xin, Geldenhuys, Werner J., Pink, John J., Dowlati, Afshin, Xu, Yan, Zhou, Aimin, Su, Bin

Journal:

Journal of Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 2.66 MB

english, 2013

39

Phase II trial of Sorafenib in conjunction with chemotherapy and as maintenance therapy in extensive-stage small cell lung cancer

Sharma, Neelesh, Pennell, Nathan, Nickolich, Myles, Halmos, Balazs, Ma, Patrick, Mekhail, Tarek, Fu, Pingfu, Dowlati, Afshin

Journal:

Investigational New Drugs

Year:

2014

Language:

english

File:

PDF, 194 KB

english, 2014

40

Clinical Trial Design in Small Cell Lung Cancer: Surrogate End Points and Statistical Evolution

Nickolich, Myles, Babakoohi, Shahab, Fu, Pingfu, Dowlati, Afshin

Journal:

Clinical Lung Cancer

Year:

2014

Language:

english

File:

PDF, 278 KB

english, 2014

41

Radiochemotherapy plus 3-aminopyridine-2-carboxaldehyde thiosemicarbazone (3-AP, NSC #663249) in advanced-stage cervical and vaginal cancers

Kunos, Charles A., Radivoyevitch, Tomas, Waggoner, Steven, Debernardo, Robert, Zanotti, Kristine, Resnick, Kimberly, Fusco, Nancy, Adams, Ramon, Redline, Raymond, Faulhaber, Peter, Dowlati, Afshin

Journal:

Gynecologic Oncology

Year:

2013

Language:

english

File:

PDF, 593 KB

english, 2013

42

Combined SCLC Clinical and Pathologic Characteristics

Babakoohi, Shahab, Fu, Pingfu, Yang, Michael, Linden, Philip A., Dowlati, Afshin

Journal:

Clinical Lung Cancer

Year:

2013

Language:

english

File:

PDF, 483 KB

english, 2013

43

A Phase I Study of the combination of oxaliplatin/docetaxel and vandetanib for the treatment of advanced gastroesophageal cancer

Halmos, Balazs, Jia, Yuxia, Bokar, Joseph A., Fu, Pingfu, Adelstein, David J., Juergens, Rosalyn, Rodal, Mary Beth, Dowlati, Afshin

Journal:

Investigational New Drugs

Year:

2013

Language:

english

File:

PDF, 149 KB

english, 2013

44

Randomized phase II trial of sorafenib alone or in combination with carboplatin/paclitaxel in women with recurrent platinum sensitive epithelial ovarian, peritoneal, or fallopian tube cancer

Schwandt, Anita, Gruenigen, Vivian E., Wenham, Robert M., Frasure, Heidi, Eaton, Susan, Fusco, Nancy, Fu, Pingfu, Wright, John J., Dowlati, Afshin, Waggoner, Steven

Journal:

Investigational New Drugs

Year:

2014

Language:

english

File:

PDF, 374 KB

english, 2014

45

Dual VEGF/VEGFR inhibition in advanced solid malignancies

Mittal, Kriti, Koon, Henry, Elson, Paul, Triozzi, Pierre, Dowlati, Afshin, Chen, Helen, Borden, Ernest C, Rini, Brian I

Journal:

Cancer Biology & Therapy

Year:

2014

Language:

english

File:

PDF, 900 KB

english, 2014

46

PIAS3 activates the intrinsic apoptotic pathway in non-small cell lung cancer cells independent of p53 status

Dabir, Snehal, Kluge, Amy, McColl, Karen, Liu, Yu, Lam, Minh, Halmos, Balazs, Wildey, Gary, Dowlati, Afshin

Journal:

International Journal of Cancer

Year:

2014

Language:

english

File:

PDF, 508 KB

english, 2014

47

A Phase II Trial of Fosbretabulin in Advanced Anaplastic Thyroid Carcinoma and Correlation of Baseline Serum-Soluble Intracellular Adhesion Molecule-1 with Outcome

Mooney, Colin J., Nagaiah, Govardhanan, Fu, Pingfu, Wasman, Jay K., Cooney, Matthew M., Savvides, Panos S., Bokar, Joseph A., Dowlati, Afshin, Wang, Ding, Agarwala, Sanjiv S., Flick, Susan M., Hartman

Journal:

Year:

2009

Language:

english

File:

PDF, 124 KB

english, 2009

48

Phase II Trial of Sorafenib in Patients with Advanced Anaplastic Carcinoma of the Thyroid

Savvides, Panayiotis, Nagaiah, Govardhanan, Lavertu, Pierre, Fu, Pingfu, Wright, John J., Chapman, Robert, Wasman, Jay, Dowlati, Afshin, Remick, Scot C.

Journal:

Year:

2013

Language:

english

File:

PDF, 133 KB

english, 2013

49

Defining Subgroups of Small-Cell Lung Cancer

Dowlati, Afshin, Wildey, Gary

Journal:

Journal of Thoracic Oncology

Year:

2014

Language:

english

File:

PDF, 139 KB

english, 2014

50

RET Mutation and Expression in Small-Cell Lung Cancer

Dabir, Snehal, Babakoohi, Shahab, Kluge, Amy, Morrow, James J., Kresak, Adam, Yang, Michael, MacPherson, David, Wildey, Gary, Dowlati, Afshin

Journal:

Journal of Thoracic Oncology

Year:

2014

Language:

english

File:

PDF, 903 KB

english, 2014

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